Patient-Matched Technology Shows Value for Patients, Surgeons and the Healthcare System

Smith & Nephew (NYSE: SNN, LSE: SN) today announces the publication of a new study on the value of patient-matched technology for total knee replacement. Published in the Journal of Arthroplasty (JOA), the official Journal of the American Association of Hip and Knee Surgeons, this first-of-its-kind study specifically looked at the VISIONAIRE◊ patient-matched system from Smith & Nephew. To view the article, click here.

With the VISIONAIRE system, a surgeon uploads each patient's specific MRI and X-Ray images into Smith & Nephew's proprietary web-based software. A Smith & Nephew engineer then uses this data to design and build customized surgical instruments that accommodate the unique shapes and angles of each patient's joint for a more precisely aligned implant.

According to the JOA study, surgeries that used patient-matched instruments resulted in implants that were a full degree closer to neutral - the body's natural alignment - than those using traditional instrumentation. The accurate placement of an implant has been shown to reduce implant wear and improve the longevity of an implant. ⁱ

Additional key findings in the study are that patient-matched technology:
• Reduces the amount of time a patient spent under anaesthesia;
• Shortens a patient's hospital stay;
• Shortens the length of the incision required for knee replacement surgery.

Also, because patient-matched technology reduces the number of instrument trays required by 43% and eliminates more than 20 surgical steps for each surgery ⁱⁱ, it may reduce hospital expenses related to total knee replacements by cutting sterilization costs and increasing OR efficiency.

“Patient-matched technology is driving a shift in thinking for our entire industry,” says Scott Elliott, SVP of Smith & Nephew's Global Knee Franchise. “This study clearly shows that VISIONAIRE patient-matched technology improves outcomes for patients, simplifies the OR experience for surgeons and pulls cost out of the healthcare system.”

“Our position as leaders in patient-matched technology is clear,” says Elliott. “Moving forward, we'll continue to meet the growing demand for VISIONAIRE instrumentation as we simultaneously develop new applications for its use across our entire portfolio.”

Smith & Nephew is a global medical technology business with global leadership positions in Orthopaedic Reconstruction, Advanced Wound Management, Sports Medicine, Trauma and Clinical Therapies. The Company has distribution channels, purchasing agents and buying entities in over 90 countries worldwide. Annual sales in 2010 were nearly $4.0 billion.

Smith & Nephew is dedicated to helping improve people's lives. The Company prides itself on the strength of its relationships with its surgeons and professional healthcare customers, with whom its name is synonymous with high standards of performance, innovation and trust.

This press release contains certain "forward-looking statements" within the meaning of the U.S. Private Securities Litigation Reform Act of 1995. In particular, statements regarding planned growth in our business and in our operating margins discussed under "Outlook" are forward-looking statements as are discussions of our product pipeline. These statements, as well as the phrases "aim", "plan", "intend", "anticipate", "well-placed", "believe", "estimate", "expect", "target", "consider" and similar expressions, are generally intended to identify forward-looking statements. Such forward-looking statements involve known and unknown risks, uncertainties and other important factors (including, but not limited to, the outcome of litigation and regulatory approvals) that could cause the actual results, performance or achievements of Smith & Nephew, or industry results, to differ materially from any future results, performance or achievements expressed or implied by such forward-looking statements. Please refer to the documents that Smith & Nephew has filed with the U.S. Securities and Exchange Commission under the U.S. Securities Exchange Act of 1934, as amended, including Smith & Nephew's most recent annual report on Form 20F, for a discussion of certain of these factors.

All forward-looking statements in this press release are based on information available to Smith & Nephew as of the date hereof. All written or oral forward-looking statements attributable to Smith & Nephew or any person acting on behalf of Smith & Nephew are expressly qualified in their entirety by the foregoing. Smith & Nephew does not undertake any obligation to update or revise any forward-looking statement contained herein to reflect any change in Smith & Nephew's expectation with regard thereto or any change in events, conditions or circumstances on which any such statement is based.

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